These reactions may include bloating, anxiety, nausea, constipation, and sleeplessness along with making you all sweaty and jittery. Nursing considerations Assessment. Xanthines also stimulate muscle and cardiac cells and neurons. The rate and range of febuxostat side effects are low at doses of up to 120 mg and only increase with a daily dose of over 120 mg. Xanthine is found to be associated with Lesch-Nyhan syndrome and xanthinuria type 1, which are inborn errors of metabolism. Concomitant treatment with xanthine derivatives, steroids, or diuretics may potentiate any hypokalemic effect of formoterol Use with caution in patients taking non-potassium-sparing diuretics, as the ECG changes and/or hypokalemia may worsen with concomitant beta 2 -agonists The molar mass of the compound is 266.25 g/mol. 5.7 Xanthine derivatives. The vasodilation caused by xanthines has been used to treat intermittent claudication (pentoxifylline). Author information: (1)Center for Multidisciplinary Studies, University of Belgrade, 29 Novembra 142, 11000, Belgrade, Yugoslavia. Uses and Benefits of Doxofylline: 57. Stimulates breathing and has a high therapeutic index with fewer side effects than theophylline. It is worth noting that members of this series lack the carboxylic acid to interact with Arg111 of GPR109A, unlike compounds in the aforementioned series. The incidence of severe side effects was much less frequent than mild side effects (1.2–3.8% to 20.1–38.7%). The publications reveal no age-dependent increase in side effects for febuxostat. Are There Any PX Pro Xanthine Side Effects? The functional role of Doxofylline is similar to that of Theophylline but with fewer side-effects. PX Pro Xanthine is a great weight loss product which has proven results from a lot of people. See "What Are Side Effects Associated with Using Zaditen?" Therefore, monitoring for nontoxic levels is necessary. 56. Xanthine derivatives have been used in allergic asthma for their bronchodilatory and anti-inflammatory properties; however, these agents have multiple side effects. Smoking cigarettes or other tobacco products may markedly influence the effects of theophylline. Many xanthine bronchodilator users experience no, or minor, side effects, particularly if serum theophylline levels are less than 20 mcg/mL. A xanthine series (I) exemplified by 33 and 34 is another important class of GPR109A agonists [83–88]. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. Traditional asthma medications such as theophylline have less of a role in the treatment of pure exercise-induced asthma. Long-Term Effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy, and individual susceptibility. Why is theophylline classified as a bronchodilator? Xanthine derivatives (eg, theophylline) because side effects, including risk of nausea, vomiting, heart problems, or seizures, may be increased by thiabendazole; This may not be a complete list of all interactions that may occur. Hypersensitivity to xanthine derivatives, porphyria. Andjus RK(1), Konjević D, Damjanović I, Gacić Z. What are the three main physiological effects produced by xanthines? In patients with The product, however, causes extreme allergic reactions in some cases. Side Effects: Every drug is capable of producing side effects. Cautions. Effects of xanthine derivatives on electroretinographic responsiveness. Yes! It is … It has a relaxing effect on bronchial smooth muscles. The chemical formula of Doxofylline is C11H14N4O4. Ask your health care provider if thiabendazole may interact with other medicines that you take. The active ingredient in the drug is the compound Doxofylline that is a Xanthine derivative. See "What Are Side Effects Associated with Using Zaditen?" 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